Pure Encapsulations Nitric Oxide Ultra


SKU: PENO1 Category:


Nitric Oxide Ultra (capsules) offers a blend of CranLoad® and citrulline to support healthy blood flow by targeting nitric oxide production and flow-mediated dilation. The formula centers around CranLoad®, a novel fruit blend developed as part of an extensive research program with the Institute of Nutrition and Functional Foods (INAF) and Université Laval in Quebec, Canada. CranLoad® delivers a unique cranberry and grape seed blend that has been the subject of several trials. Cranberries and grapes are particularly generous sources of proanthocyanidins and other polyphenols.

In addition to being antioxidants, these compounds offer specific vascular support mechanisms that are associated with enhanced endothelial function. Research indicates that CranLoad® provides statistically significant support for healthy flow-mediated dilation (FMD), an effect similar to arginine administration. FMD reflects blood vessel dilation mediated by nitric oxide synthase (NOS), an enzyme that generates the endogenous vasodilator, nitric oxide. In one study, the peak increase in brachial artery diameter following CranLoad® supplementation was 2.8% at 60 minutes.

A similar physiological effect has been demonstrated with arginine. Citrulline is included to support nitric oxide production in the blood vessel endothelium and other tissues. Research indicates that citrulline increases plasma arginine in a dose-dependent manner and to a greater degree than arginine supplementation.*

Serving Size:2 Capsule
Servings Per Container:60
                                                                                                                                        Amount Per Serving
L-Citrulline (free form)                                                                                                          1000 mg
CranLoad™ proprietary blend providing                                                                                382 mg
cranberry (vaccinium macrocarpon) extract (fruit grape (vitis vinifera) extract (seed)
Other Ingredients: vegetarian capsule (cellulose, water), ascorbyl palmitate
This product is gluten free and non-GMO.
Each bottle contains 120 capsules.

Additional information

Weight .3 lbs
Dimensions 3 × 3 × 5 in